Germany has limited the use of the Oxford-AstraZeneca COVID-19 vaccine to people 60 years of age and older due to concerns that it may be causing blood clots.   Federal and state health authorities cited nearly three-dozen cases of blood clots known as cerebral sinus vein thrombosis in its decision Tuesday, including nine deaths.  The country’s medical regulator, the Paul Ehrlich Institute, says all but two of the cases involved women between the ages of 20 and 63.    The nationwide order was made after several local governments, including Berlin, Munich and the states of Brandenburg and North Rhine-Westphalia, had already decided to limit the Oxford-AstraZeneca vaccine to older residents.   Health authorities say younger people who belong to a high-risk category for serious illness from COVID-19 can still get the vaccine, while people 60 and younger who have received the first dose of the Oxford-AstraZeneca shot can still receive the second shot as planned. About 2.7 million Germans have been inoculated with the vaccine. The decision is likely to further slow down Germany’s already sluggish vaccination campaign, and marks another setback for the Oxford-AstraZeneca vaccine, which has had a troubled rollout across the world. Several European countries had briefly stopped use of the Oxford-AstraZeneca vaccine because of similar reports of blood clots, until the  European Medicines Agency (EMA), the European Union’s drug approval body, declared the vaccine as safe.German Chancellor Angela Merkel, right, and Health Minister Jens Spahn brief the media after a virtual meeting with federal state governors at the chancellery in Berlin, Germany, March 30, 2021.Germany’s decision came a day after Canada said it would stop offering the Oxford-AstraZeneca vaccine to people under age 55 because of concerns of serious blood clots, especially among younger women.   Also on Tuesday, the United States and 13 other nations issued a statement raising “shared concerns” about the newly released World Health Organization report on the origins of the virus that causes COVID-19. The statement, released on the U.S. State Department website, as well as the other signatories, said it was essential to express concerns that the international expert study on the source of the virus was significantly delayed and lacked access to complete, original data and samples. The WHO formally released its report earlier Tuesday, saying while the report presents a comprehensive review of available data, “we have not yet found the source of the virus.”  The team reported difficulties in accessing raw data, among other issues, during its visit to the city of Wuhan, China earlier this year. The researchers also had been forced to wait days before receiving final permission by the Chinese government to enter Wuhan. The joint statement by the United States and others went on to say, “scientific missions like these should be able to do their work under conditions that produce independent and objective recommendations and findings.”  The nations expressed their concerns in the hope of laying “a pathway to a timely, transparent, evidence-based process for the next phase of this study as well as for the next health crisis.” Along with the United States, the statement was signed by the governments of Australia, Britain, Canada, the Czech Republic, Denmark, Estonia, Israel, Japan, Latvia, Lithuania, Norway, the Republic of Korea, and Slovenia. WHO Director-General Tedros Adhanom Ghebreyesus said Tuesday further study and more data are needed to confirm if the virus was spread to humans through the food chain or through wild or farmed animals.   Tedros said that while the team has concluded that a laboratory leak is the least likely hypothesis, the matter requires further investigation. WHO team leader Peter Ben Embarek told reporters Tuesday that it is “perfectly possible” COVID-19 cases were circulating as far back as November or October 2019 around Wuhan, earlier than has been documented regarding the spread of the virus. 
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